Hidden Threat: Breast Cancer Cells Lurk for Years Before Relapse

Breast cancer cells can remain hidden in the body for years before resurfacing. This alarming finding was highlighted in a study led by Dr. Gary Luker from the University of Michigan. It reveals the crafty ways cancer cells evade detection and cause relapse.

Cancer Cells Stay Dormant

The study shows that estrogen receptor-positive breast cancer cells can stay dormant for years or decades. They often hide in the bone marrow, waiting to become active again. These cells resist treatment and pose a long-term threat to survivors.

How Cancer Cells Survive

Researchers found that a protein called GIV (Girdin) plays a crucial role in these cells’ survival. GIV makes the cells resistant to estrogen-targeted therapies like Tamoxifen.

Additionally, the cancer cells use cellular tunnels to borrow proteins from bone marrow stem cells. This process helps them grow stronger and resist treatments.

Key Findings

A Call for Better Treatments

Dr. Luker explained that cancer cells borrow molecules like proteins and RNA from mesenchymal stem cells. This borrowing makes them more aggressive and resistant to drugs.

The study emphasizes the need for innovative treatments targeting these crafty cancer cells. Such therapies could neutralize dormant cells and prevent breast cancer relapses.

What This Means for Patients

The findings highlight the importance of regular follow-ups and advanced treatment plans. By understanding how these cells survive, researchers hope to develop strategies that prevent relapses and offer long-term protection.

Disclaimer: This article is for informational purposes only. Always consult a medical professional i.e. Doctor for advice on health conditions.

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